Allergies in a dental office
Reports of true allergic reactions to local anaesthetics are uncommon. Investigation finds most of these reactions to be of psychogenic origin. A confirmed allergy to an amide is rare; the ester topical procaine is somewhat more allergenic. An allergy to one ester rules out using another ester, as the allergenic component is the breakdown product para-aminobenzoic acid (PABA), and all esters are metabolized to this product. Conversely, an allergy to one amide does not rule out using another amide. Epinephrine has not been shown to have any serious allergenic potential.
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About the Author
Haynes Darlington M.Sc. PharmD. (CCPE) joined the pharmaceutical industry in 1969 on the medical side. In 1982 he was selected to the dental team to make submissions to regulatory agencies (FDA) and HC (Health Canada) to obtain acceptance for Articaine hcl into North America for Dental use as a local anesthetic. He is highly respected among peers in the field of pharmacology and bio-chemistry. In 1999, Haynes received The Team Excellence Award from The City of New York. The award recognized the value and professionalism of a continuing education program.
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